The Isolation of a New S-Methyl Benzothioate Compound from a Marine-Derived Streptomyces sp.
نویسندگان
چکیده
The application of an HPLC bioactivity profiling/microtiter plate technique in conjunction with microprobe NMR instrumentation and access to the AntiMarin database has led to the isolation of a new 1. In this example, 1 was isolated from a cytotoxic fraction of an extract obtained from marine-derived Streptomyces sp. cultured on Starch Casein Agar (SCA) medium. The 1D and 2D (1)H NMR and ESIMS data obtained from 20 μg of compound 1 fully defined the structure. The known 2 was also isolated and readily dereplicated using this approach.
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عنوان ژورنال:
دوره 2012 شماره
صفحات -
تاریخ انتشار 2012