Studies of sebum. IV. The estimation of squalene in sebum and sebum-like materials.
نویسنده
چکیده
منابع مشابه
Studies of sebum. VIII. Observations on the squalene and cholesterol content and the possible functions of squalene in human sebum.
The object of our investigations has been to study the composition ofsebum and to elucidate its role in maintaining the health of the skin. In a previous paper on the hydrocarbons of sebum (Boughton, Hodgson-Jones, MacKenna, Wheatley & Wormall, 1955) we observed that the squalene content of sebum showed wide variations, both in samples collected from the same subject on different occasions and ...
متن کاملSebaceous gland lipids.
The principal activity of mature sebaceous glands is producing and secreting sebum, which is a complex mixture of lipids. Sebum composition is different among species and this difference is probably due to the function that sebum has to absolve. In human sebum there are unique lipids, such as squalene and wax esters not found anywhere else in the body nor among the epidermal surface lipids. Mor...
متن کاملSebum/Meibum Surface Film Interactions and Phase Transitional Differences
PURPOSE Sebum may contribute to the composition of the tear film lipid layer naturally or as a contaminant artifact from collection. The aims of this study were to determine: if sebum changes the rheology of meibum surface films; if the resonance near 5.2 ppm in the 1H-NMR spectra of sebum is due to squalene (SQ); and if sebum or SQ, a major component of sebum, interacts with human meibum. ME...
متن کاملThe possible role of squalene as a protective agent in sebum.
Human sebum contains squalene, which is a polyunsaturated triterpenoid hydrocarbon (2, 7). This substance constitutes approximately 5 per cent of skin surface sebum of the adult (2). Oxygen is taken up avidly when squalene is ex posed to air, with the rapid formation of peroxides. This fact suggested that it might function as a protective agent in sebum. It has been demon strated that it is fun...
متن کاملThe Hong Kong Society of Dermatology and Venereology Annual Scientific Meeting 2010
Sebum is secreted by sebaceous gland via holocrine secretion. It contains free fatty acid, wax and sterol esters, tr iglycerides and squalene. The sebaceous glands are distributed mainly at scalp, face, upper back and chest. The secretion of sebum is influenced by androgen and is increased at the time of puberty. There is also diurnal and seasonal variation. The sebum may increase in the mornin...
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ورودعنوان ژورنال:
- The Biochemical journal
دوره 55 4 شماره
صفحات -
تاریخ انتشار 1953