Glutamate levels in the anterior cingulate cortex correlate with self-reported impulsivity in patients with borderline personality disorder and healthy controls

نویسندگان

  • M. Hoerst
  • W. Weber-Fahr
  • N. Tunc-Skarka
  • M. Ruf
  • M. Bohus
  • C. Schmahl
  • G. Ende
چکیده

Introduction: Stress associated impulsivity belongs to the key features of borderline personality disorder (BPD) and can be regarded as a form of executive dysfunction. The anterior part of the cingulate cortex has been characterized as “executive” in function, whereas the posterior region is characterized as “evaluative” [1]. Therefore, the anterior cingulate cortex (ACC) was chosen as the region of interest for single voxel proton magnetic resonance spectroscopy (H MRS) to investigate whether its metabolism may modulate impulsivity.

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تاریخ انتشار 2009