Enzymatic synthesis of the maltose analogues, glucosyl glucosamine, glucosyl N-acetyl-glucosamine and glucosyl 2-deoxyglucose by an extract of Neisseria perflava.

Since xylose could be substituted for glucose to yield 4-0-a-Dglucosyl n-xylose (a), it seemed possible that the enzyme could be used for the synthesis of yet other disaccharides possessing the a-l,4 linkage. The present communication demonstrates that glucosamine, N-acetylglucosamine, and 2-deoxyglucose can indeed serve as substrates to yield the corresponding maltose analogues. The preparation of these new disaccharides and some of their properties are also reported.