Iso-Osmolar versus Low-Osmolar Contrast Media in Reducing Contrast Induced Nephropathy in Patient with Renal Impairment Undergoing Coronary Angiography
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Contrast media induced nephropathy: CONTRAST There is an ongoing controversy on the impact of iso- osmolar contrast agents on contrast media induced nephropathy (CIN). The COntrast Media and Neph- roToxicity Following Coronary Revascularization by AngioplaSTy
There is an ongoing controversy on the impact of isoosmolar contrast agents on contrast media induced nephropathy (CIN). The COntrast Media and NephroToxicity Following Coronary Revascularization by AngioplaSTy (CONTRAST) randomized 324 patients with impaired renal function undergoing PCI to receive either the iso-osmolar contrast medium iodixanol 320 (Visipaque ) or the low-osmolar contrast me...
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متن کاملNephrotoxicity of iodixanol versus ioversol in patients with chronic kidney disease: the Visipaque Angiography/Interventions with Laboratory Outcomes in Renal Insufficiency (VALOR) Trial.
BACKGROUND Iso-osmolar contrast medium iodixanol has been reported to be less nephrotoxic than selected low-osmolar contrast media (LOCM) in chronic kidney disease (CKD) patients with diabetes mellitus. This study compared the nephrotoxicity of iodixanol and the LOCM ioversol in CKD patients undergoing coronary angiography. METHODS This is a prospective double-blind trial in 337 patients with...
متن کاملComparison of iodixanol and ioversol for the prevention of contrast-induced nephropathy in diabetic patients after coronary angiography or angioplasty.
INTRODUCTION AND OBJECTIVES This study was designed to compare differences in the incidence of contrast-induced nephropathy (CIN) and changes in serum creatinine (SCr) level following iso-osmolar iodixanol or low-osmolar ioversol administration in diabetic patients undergoing coronary angiography, with or without percutaneous coronary intervention (PCI). A number of studies have indicated that ...
متن کاملChoice of contrast medium in patients with impaired renal function undergoing percutaneous coronary intervention.
BACKGROUND No clinical trial has yet focused on contrast-mediated nephrotoxicity in patients with chronic renal failure exclusively undergoing percutaneous coronary intervention (PCI). Therefore, the aim of this study was to compare the effect of contemporary contrast media on nephrotoxicity in this high-risk patient population. METHODS AND RESULTS This prospective, randomized, double-blind, ...
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