CALL FOR PAPERS Epigenetics and Epigenomics Differential methylation in visceral adipose tissue of obese men discordant for metabolic disturbances
نویسندگان
چکیده
Frédéric Guénard, André Tchernof, Yves Deshaies, Louis Pérusse, Simon Biron, Odette Lescelleur, Laurent Biertho, Simon Marceau, and Marie-Claude Vohl Institute of Nutrition and Functional Foods (INAF); Department of Food Science and Nutrition, Laval University, Québec, Canada; Endocrinology and Nephrology, CHU de Québec Research Center, Québec, Canada; Québec Heart and Lung Institute, Québec, Canada; Department of medicine, Laval University, Québec, Canada; Division of Kinesiology, Department of Social and Preventive Medicine, Laval University, Québec, Canada; and Department of Surgery, Laval University, Québec, Canada
منابع مشابه
Differential methylation in visceral adipose tissue of obese men discordant for metabolic disturbances.
Obesity is associated with an increased risk of Type 2 diabetes and cardiovascular diseases (CVD). The severely obese population is heterogeneous regarding CVD risk profile. Our objective was to identify metabolic pathways potentially associated with development of metabolic syndrome (MetS) through an analysis of overrepresented pathways from differentially methylated genes between severely obe...
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Background & Aims: Physical activity by modulating angiogenesis in adipose tissue, effects on the entire body metabolic profile. Therefore, the aim of this study was to investigate the effect of 12 weeks of moderate intensity continuous training on VEGF, PEDF and PAI-1 of visceral and subcutaneous adipose tissue in obese rats. Materials & Methods: 15 male Wistar rats were divided into 2 groups...
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Epigenetic mechanisms are known to be involved in tissue-specific differentiation. DNA methylation patterns have been shown to be largely conserved across tissues but with variation for specific genes. However, it is unclear whether the variability observed in the methylation profile of a metabolically active tissue is reflected in other sources such as hematopoietic tissue. This study aimed to...
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Introduction: Omentin, an adipokine, with anti-inflammatory effects reduces insulin resistance, and can hence, play an important role in prevention of cardiovascular disease and diabetes. The present study aimed to investigate the association of plasma and dietary fatty acids with gene expression of omentin in visceral and subcutaneous adipose tissues. Materials and Methods: Visceral and subcut...
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Objective: Reducing white adipose tissue is an important strategy for treatment of obesity and its related metabolic disorders. The purpose of this study was to determine the effect of endurance exercise and adenosine consumption on the expression of selected genes of thermogenic pathway in the visceral adipose tissue of obese male rats. Materials and Methods: Twenty male wistar rats were fed ...
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