Arf 6 promotes autophagosome formation via effects on phosphatidylinositol 4 , 5 - bisphosphate and phospholipase
نویسنده
چکیده
The Rockefeller University Press $30.00 J. Cell Biol. Vol. 196 No. 4 483–496 www.jcb.org/cgi/doi/10.1083/jcb.201110114 JCB 483 K. Moreau and B. Ravikumar contributed equally to this paper. Correspondence to David C. Rubinsztein: [email protected] Abbreviations used in this paper: 5ase, 5-phosphatase; Arf, ADP ribosylation factor; ARNO, Arf nucleotide binding site opener; Baf A1, bafilomycin A1; CTX, cholera toxin; FKBP, FK506-binding protein; FRB, FKBP12-rapamycin binding; GEEC, GPi-enriched endocytic compartment; GPi, glycosylphosphatidylinositol; MEF, mouse embryonic fibroblast; MHC, major histocompatibility complex; mRFP, monomeric RFP; mTOR, mammalian target of rapamycin; PAS, preautophagic structure; PH, pleckstrin homology; PIP2, phosphatidylinositol 4,5-bisphosphate; PIP5K, phosphatidylinositol 4-phosphate 5-kinase. Introduction
منابع مشابه
Arf6 promotes autophagosome formation via effects on phosphatidylinositol 4,5-bisphosphate and phospholipase D
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