Integrative Modeling of Mitochondrial Metabolism
نویسندگان
چکیده
We are in the process of constructing a kinetic model of mitochondrial metabolism including the electron transport (respiratory chain), the TCA cycle, the fatty acid metabolism (β oxidation), the inner-membrane metabolite carriers, the protein carriers, and the mitochondrial gene expression system. In this work, we report a model of these metabolic pathways that has been recently completed using the E-CELL system [2], a generic simulation environment for cellular simulation based on multiple ordinary differential equations.
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