Direct observation of single RNA polymerase processing through a single endogenous gene in a living yeast cell.
نویسندگان
چکیده
Rapid advances in live-cell imaging have now enabled direct observation of the transcription of single nascent mRNA molecules from an endogenous yeast gene. A novel quantitative fluctuation analysis of fluorescently labeled mRNA revealed the kinetics of transcription initiation and the dynamics of elongation and termination.
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ورودعنوان ژورنال:
- Angewandte Chemie
دوره 50 42 شماره
صفحات -
تاریخ انتشار 2011