Polyglandular Autoimmune Syndromes (pga)
نویسندگان
چکیده
Definition of PGA PGA involve multiple endocrine gland insufficiencies (minimum two), being frequently associated with diseases of non-endocrine organs, and occur in individual patients and their families.1,2 The autoimmune endocrine associations recognise more generics: autoimmune polyglandular syndromes (APS), autoimmune polyendocrine disease (APD), polyglandular failure syndromes (PFS), and polyglandular deficiency syndromes (PDS). In the association of multiple endocrine diseases, one or more entities may present a subclinical form. Classification of PGA and its components is presented in Tables 1 and 2. Besides the classical entities of patients with Addisons disease, there are groups sometimes referred to as autoimmune polyglandular syndrome POLYGLANDULAR AUTOIMMUNE SYNDROMES (PGA)
منابع مشابه
Erythema annulare centrifugum: association with autoimmune polyglandular syndrome type 1
Autoimmune polyendocrine syndromes are a heterogeneousgroup of rare diseases characterized by autoimmune activityagainst more than one endocrine organ, although non-endocrineorgans can also be affected. We report the association of APS Iwith erythema annulare centrifugum in an 18-years-old male whopresented with multiple figurate erythema spreading on his trunkand extremities along with a histo...
متن کاملA Rare Association in a Case of Autoimmune Polyglandular Syndrome
Autoimmune polyglandular syndromes (APS) bring together immune mediated disease of endocrine and nonendocrine organs that manifest in an individual lifelong. On the basis of the genetic errors involved and the association of autoimmune disorders, autoimmune polyglandular syndromes are classified in two different groups: APS type I and type II. Sometimes a rare association of autoimmune disorder...
متن کاملDiffuse alveolar hemorrhage due to antibasement membrane antibody disease appearing with a polyglandular autoimmune syndrome.
We describe a patient with type 3-C polyglandular autoimmune syndrome who presented with diffuse alveolar hemorrhage and normal renal function. The diagnosis of antibasement membrane antibody disease was established by immunofluorescent staining of transbronchial biopsy specimens. We suggest the incorporation of antibasement membrane antibody disease into the spectrum of diseases that define th...
متن کامل[Case report of sister with Duane's syndrome and PGA, or myasthenia gravis].
We report a case of polyglandular autoimmune syndrome (PGA) complicated by Duane's syndrome. The patient was 44-year-old female with marked limitation of abduction in the left eye, lethargy, nonhomogeneous facial pigmentation, goiter, and oligomenorrhea. A diagnosis of chronic thyroiditis was first made to explain the patient's symptoms. Laboratory examinations were performed. Plasma ACTH level...
متن کاملAutoimmune Polyglandular Syndrome Type 2 (APS-2) in a 70-Year-Old Woman: A Case Report
Type2 autoimmune polyglandular (Schmidt) syndrome is defined by the occurrence of at least 2 out of 3 of the following manifestations, Addison's disease, Hypothyroidism and Type 1 diabetes mellitus. APS2 is a rare condition with an incidence of 1–2/100 000 per year. Prevalence of APS-2 is most happening in the range of 20-40 years of age. Here we present a patient who complained about loss of ...
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