Nuclear Pores Set the Speed Limit for Mitosis
نویسندگان
چکیده
The spindle assembly checkpoint prevents separation of sister chromatids until each kinetochore is attached to the mitotic spindle. Rodriguez-Bravo et al. report that the nuclear pore complex scaffolds spindle assembly checkpoint signaling in interphase, providing a store of inhibitory signals that limits the speed of the subsequent mitosis.
منابع مشابه
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ورودعنوان ژورنال:
- Cell
دوره 156 شماره
صفحات -
تاریخ انتشار 2014