In vitro Antioxidant Potential of Pure Fractions of Eclipta alba
نویسندگان
چکیده
Oxidative stress and Ultraviolet (UV) irradiation-induced skin damage, is involved in numerous diseases. Eclipta alba which belongs to Asteraceae family is used traditionally in Ayurvedic system of medicine in India for the treatment of liver diseases. Our study shows that water extract of E. alba has a potent effect in scavenging 1, 1-diphenyl-2-picrylhydrazyl (DPPH), chelating ferrous ion, and superoxide radicals, exhibiting IC50 values of 0.21 mg/mL, 1.20 mg/mL, and .49 mg/mL, respectively. Identification and quantification of the wedelolactone, one of the active constituents of the Eclipta alba plant extract, was carried out by HPLC analysis. The result of the present study indicates that the Eclipta alba extract shows a high amount of ascorbic acid, tannins, flavonoids, phenolics, contents. The hydroalcoholic extract of Eclipta alba effectively scavenged free radicals at all different concentrations and showed potent antioxidant potency. Eclipta alba extract shows antioxidative properties.
منابع مشابه
Antioxidant Activity of Eclipta alba L. in Normal Rat Liver
The present study investigates the antioxidant potential of the ethyl acetate fraction of the aerial parts Eclipta alba L. Hassk (EAEA) which was widely used as hepatoprotective plant. EAEA was orally administered at doses of 50, 100 and 200 mg/kg for 7 days in male Charles Foster rats. The extent of hepatoprotective potential of E . alba was studied by assessing the biochemical para...
متن کاملAlcoholic Extract of Eclipta alba Shows In Vitro Antioxidant and Anticancer Activity without Exhibiting Toxicological Effects
As per WHO estimates, 80% of people around the world use medicinal plants for the cure and prevention of various diseases including cancer owing to their easy availability and cost effectiveness. Eclipta alba has long been used in Ayurveda to treat liver diseases, eye ailments, and hair related disorders. The promising medicinal value of E. alba prompted us to study the antioxidant, nontoxic, a...
متن کاملEclipta Alba Ameliorates Carbon Tetrachloride-induced Lipid Peroxidation: an in Vitro Study
The present investigation was an attempt to evaluate the possible ameliorative effect of Eclipta alba on carbon tetrachloride (CCl4) – induced lipid peroxidation in liver of mice in vitro. Antioxidant activity of medicinally important plant Eclipta alba was determined by DPPH – radical scavenging activity. Liver tissue was collected from healthy Swiss albino female mice weighing 30-35 gm. Liver...
متن کاملIn vitro antioxidant activity of berry (Morus alba var.nigra)
Antioxidant activity of Berry (Morus alba var. nigra) was investigated. For superoxide anion radical assay, the superoxide anion radicals were generated by a pyrogallol auto oxidation system, Nitric oxide radical inhibition by the use of Griess Illosvoy reaction and reducing power was determined according to the Oyaizu method. At least this sample was represented a potential antioxidant capacit...
متن کاملScreening of Leaves and Roots of Eclipta alba for Hepatoprotective Activity
Leaves and roots are used as hepatic tonic rejuvenates hair, cirrhosis, ear aches, hepatitis, headache and enlarged spleen. Studies on the hepatoprotective activity on methanolic extract and sub fractions of leaves and the chloroform extract and sub fractions of roots of Eclipta alba was carried out using carbon tetrachlorideinduced liver damage and Lysosomal enzymes level in wistar albino rats...
متن کامل