Isothermal detection of RNA with restriction endonucleases.

نویسندگان

  • Lei Yan
  • Shizuka Nakayama
  • Saron Yitbarek
  • Isabel Greenfield
  • Herman O Sintim
چکیده

Herein, we demonstrate how to detect nucleic acids that do not contain restriction endonuclease recognition sites with restriction endonucleases. We show that the topology of DNA probes used in this detection strategy remarkably affects the efficiency of RNA/DNA detection.

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عنوان ژورنال:
  • Chemical communications

دوره 47 1  شماره 

صفحات  -

تاریخ انتشار 2011