Isolation of a potent anti-MRSA sesquiterpenoid quinone from Ulmus davidiana var. japonica.
نویسندگان
چکیده
A highly potent anti-MRSA sesquiterpenoid has been isolated from Ulmus davidiana var. japonica, which has been traditionally used to treat infectious diseases in Korea. This naturally occurring antibiotic was identified as mansonone F (1). This compound has been found to be highly active specifically against MRSA and showed an MIC range of 0.39-3.13 microg/ml which is comparable to that of vancomycin.
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ورودعنوان ژورنال:
- Chemical & pharmaceutical bulletin
دوره 48 11 شماره
صفحات -
تاریخ انتشار 2000