Palladium(0)-catalyzed synthesis of cyclic glucosides.
نویسندگان
چکیده
A highly regio- and stereo-selective synthesis of cyclic β-D-glucosides 3 via Pd(0)-catalyzed coupling cyclization of allenyl β-D-glucoside 1 and organic iodides in 20-38% yields is reported. After the deacetylation of 3, we obtained cyclic β-D-glucoses 4 in 90-97% yields, which may have SGLT2 inhibition activities.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 13 1 شماره
صفحات -
تاریخ انتشار 2015