ABSTRACT: BIOMATERIALS Day 2016 north carolina a&T State University

The ability to produce composite nanofibers from synthetic and natural polymers represents a significant advancement in development of composite materials with structural and material properties that will support biomedical applications such as tissue engineering, drug delivery and wound healing. In this research composite nanofiber membranes of magnesium oxide (MgO), poly (ε-caprolactone) (PCL) and chitosan (CS) was fabricated by electrospinning. A blend solution of MgO, PCL and CS was first prepared with different compositions and then the solution was transformed into nanofibrous membranes. Toward the potential use of this nanofibrous membrane in tissue engineering, its physicochemical properties, such as morphology, mechanical strength, and integrity in aqueous medium were studied and its cellular compatibility was determined.