Interaction of Mn(II) ions with human serum albumin.

نویسنده

  • E N Chikvaidze
چکیده

Investigation of nonspecific interactions of metal ions with proteins and studies of biological function of such complexes are of importance (Breslow 1978; Friedberg 1975). Identification of the binding centers of metal ions with proteins and determination of the binding constants are necessary to explain the transfer mechanisms of these ions by proteins. Earlier it has been shown (Lau et al. 1971; Friedberg 1975) that serum albumin is the major carrier of metal ions in the blood. The present paper is a report of a comparative spin resonance (ESR) investigation of Mn(II) ion binding with human serum albumin (HSA) and lysozyme, and the effect of pH

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عنوان ژورنال:
  • General physiology and biophysics

دوره 9 4  شماره 

صفحات  -

تاریخ انتشار 1990