Chediak-Higashi–Like Granules in Acute Promyelocytic Leukemia
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چکیده
RF: HHV-8 and multiple myeloma in the UK. Lancet 350:1144, 1997 (letter) 7. Gao S-J, Alsina M, Deng J-H, Harrison CR, Montalvo EA, Leach CT, Roodman GD, Jenson HB: Antibodies to Kaposi’s sarcomaassociated herpesvirus (human herpesvirus 8) in patients with multiple myeloma. J Infect Dis 178:846, 1998 8. Basten A, Brink R, Peake P, Adams E, Crosbie J, Hartley S, Goodnow CC: Self tolerance in the B-cell repertoire. Immunol Rev 122:5, 1991
منابع مشابه
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1. Markovic O, Markovic N: Chediak-Higashi similar granules in acute promyelocytic leukemia. Proceedings of The 9th Congress of Macedonian Physicians 2:1191, 1974 2. Markovic N, Henderson E: Subcellular morphology and prognosis of acute leukemia. Proceedings of The 4th Congress of Yugoslavian Internists 1:375, 1973 3. Akashi K, Shibuya T, Harada M, Oogami A, Teshima T, Takamatsu Y, Kikuchi M, N...
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The hypergranular type of acute promyelocytic leukemia (APL) is characterized by heavy granulation and the presence of Auer rods. These granules are usually small, azurophilic, and have the appearance of the primary granules of normal promyelocytes. There have been several reports of myeloid leukemias, including APL, with the unusual finding of large granules (inclusions) simulating the inclusi...
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The formation and fine structure of giant granules in neutrophil promyelocytes of a patient with a variant of acute myelogenous leukemia were investigated by electron microscopy. The patient presented with large lymph nodes and disseminated intravascular coagulation (DIC). By light microscopy, numerous giant granules, resembling those of Chediak-Higashi syndrome (CHS), were present, but Auer bo...
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RF: HHV-8 and multiple myeloma in the UK. Lancet 350:1144, 1997 (letter) 7. Gao S-J, Alsina M, Deng J-H, Harrison CR, Montalvo EA, Leach CT, Roodman GD, Jenson HB: Antibodies to Kaposi’s sarcomaassociated herpesvirus (human herpesvirus 8) in patients with multiple myeloma. J Infect Dis 178:846, 1998 8. Basten A, Brink R, Peake P, Adams E, Crosbie J, Hartley S, Goodnow CC: Self tolerance in the ...
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Giant round pink inclusions (congruent to 2 micrometers) were seen in neutrophilic myeloblasts, promyelocytes, and myelocytes from three patients with acute myelogenous leukemia. On preliminary examination of the bone marrow smears, these inclusions looked like ingested red blood cells in that they were pink and not azurophilic. The bone marrow specimens were processed for the electron microsco...
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