Enopeptin A, a novel depsipeptide antibiotic with anti-bacteriophage activity.

Using actinophage Bl and Streptomyces griseus as a convenient prescreening1* for antiviral substances, a new antibiotic, enopeptin A was isolated from a culture broth of Streptomyces sp. RK-1051. Strain RK-1051 was isolated from a soil sample collected in Tsuruoka city, Yamagata Prefecture, Japan, and deposited at the Fermentation Research Institute, Agency of Industrial Science and Technology, Japan, under the accession No. FERM