Effect of Phyllanthus niruri on wound healing in rats.

The whole plant of P. niruri was dried under shade and then macerated. 500 g of P. niruri was soaked in 3 litres of absolute a lcohol (Depar tment o f pharmacology , Manipa l ) . Af te r 24 hours , ex t rac t ion was star ted by ref lux condensat ion. The extract was concen t ra ted by d i s t i l l a t ion and then evaporated to dryness on a waterbath. 500 g of dr ied P. n i rur i y ie lded 85 .45 g of the alcoholic extract. The dose of P. niruri was fixed at 200 mg/kg body weight of the rat af te r doing acute toxic i ty s tudies and th is was the dose used by ear l ie r workers (3) . The suspens ion of a lcohol ic ex t rac t o f P. niruri was made in 2% gum acacia (E. Merck limited, Mumbai) in such a way that 1 ml of the suspens ion conta ined 40 mg of the e x t r a c t .