Quantitation of a slide test (Monotest) for infectious mononucleosis.
نویسندگان
چکیده
A slide test for infectious mononucleosis using formalinized horse erythrocytes (Monotest(2)) was quantitated and compared with standard differential heterophile (Davidsohn) titres performed on the same specimens. The Monotest titre parallels the standard presumptive heterophile (antisheep cell) titre in the degree of elevation, with a ratio of Monotest to heterophile titre of approximately 1 to 56. The simplicity of the quantitative slide test recommends it as a routine test for infectious mononucleosis.
منابع مشابه
An evaluation of the Monosticon rapid slide test diagnosis of infectious mononucleosis.
A new rapid slide test for the detection of infectious mononucleosis heterophile antibody has been compared with the Paul-Bunnell absorption test. Out of 200 sera, 46 were seropositive for infectious mononucleosis by the Paul-Bunnell test and 43 of these were detected by the Monosticon test; the three Monosticon-negative sera were of low titre. There was no problem with false positive reactions...
متن کاملNew slide test for infectious mononucleosis.
The rapid and simple slide test for infectious mononucleosis designed by Hoff and Bauer (1965) is designed and compared with a modified sheep-cell slide screening test (Maloney and Malzone, 1949) and the differentenial absorption technique (Davidson, 1937). The claim of Hoff and Bauer that their test is more ;specific' is substantiated. Brief clinical histories illustrate the argument.
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For many years, the Paul-Bunnell reaction (Paul and Bunnell, 1932) to demonstrate the presence of heterophile antibodies to sheep red cells has been accepted as a specific test for establishing the diagnosis of infectious mononucleosis. Stuart (1935), Bailey and Raffel (1935), and Davidsohn and Walker (1935) independently differentiated the antibodies for Forssman antigen and those of serum sic...
متن کاملMonospot: a differential slide test for infectious mononucleosis.
Sera collected from 372 patients with suspected infectious mononucleosis were examined for heterophile antibodies by the Paul-Bunnell and the Monospot test. Comparison of results showed the latter to be simple, time saving, and of sufficient specificity for routine use in the general laboratory.
متن کاملA Rapid Slide Test for Neterophile Antibody in Infectious Mononucleosis
‘SINCE the discovery by Paul and BunnelP in 1932. of the presence of heterophile . antibodies in the sera of patients with infectious mononucleosis, there has been a great deal of investigation into the nature and production of anti-sheep red cell aggulutinins.’ With the advent of the Rh factor and the subsequent discovery of blocking3 (incomplete,4 or hyperimmune5) antibody new avenues of appr...
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ورودعنوان ژورنال:
- Journal of clinical pathology
دوره 23 8 شماره
صفحات -
تاریخ انتشار 1970