Legg-Calvé-Perthes disease and the risk of injuries requiring hospitalization
نویسندگان
چکیده
BACKGROUND AND PURPOSE Previous studies have suggested that Legg-Calvé-Perthes disease (LCPD) is associated with repetitive trauma, coagulation problems and anatomical abnormalities of the blood supply to the femoral head. The hypothesis that repetitive trauma can affect the blood supply of the femoral head, leading to LCPD, is supported by an animal model. For evidence of an increased risk of repetitive trauma, we investigated whether patients with LCPD have a higher risk for severe injuries requiring hospitalization. PATIENTS AND METHODS We identified 2579 patients with LCPD in Sweden during the period 1964-2005. 13,748 individuals without LCPD were randomly selected from the Swedish general population, matched by year of birth, sex and region (control group). Cox proportional hazard regression estimated the risks. RESULTS Compared to the control group, patients with LCPD had a modestly raised hazard ratio (HR) of 1.2 (95% CI 1.1-1.3) for injury requiring hospitalization. The risks were slightly higher for soft tissue injuries (HR = 1.3, 95% CI:1.1-1.4) than for fractures (HR = 1.1, 95% CI: 1.0-1.3) and more pronounced among females. Compared to the control group, the higher risk for injury only applied to the lower extremities (HR = 1.2, 95% CI: 1.0-1.4) in patients with LCPD. INTERPRETATION Patients with LCPD are vulnerable to injuries which could be interpreted as a marker of hyperactive behavior. It could also implicate that anatomical changes in the bone formation or blood supply of the femoral head - increasing its sensibility for trauma - contribute to the etiology of LCPD.
منابع مشابه
Evolution in diagnosis and treatment of Legg-Calve-Perthes disease
Legg-Calvé-Perthes disease (LCPD) is an idiopathic osteonecrosis of the femoral head with variable complications and resultant deformity of the femoral head and osteoarthritis. Suggested risk factors are acetabular retroversion, obesity, latitude, hyperactivity, and coagulopathy. The most commonly applied classification is based on radiolucency in the lateral pillar of the femoral head, which i...
متن کاملClinical Outcome of Femoral Osteotomy in Patients with Legg-Calve´-Perthes Disease
Background: Legg-Calve´-Perthes disease is a juvenile idiopathic osteonecrosis in which the blood supply of femoral head is not sufficient and the bone dies provisionally. The aim of this study is to evaluate outcome of Femoral osteotomy in children with LCPD in our University Hospital. Methods: In a descriptive analytic study, between 2008 and 2013, patients with the diagnosis of Legg-Calv...
متن کاملEvaluation of physiotherapy in the treatment of Legg-Calvé-Perthes disease.
INTRODUCTION Physiotherapy using muscle strengthening and stretching exercises is claimed to have beneficial effects in the treatment of Legg-Calvé-Perthes disease; however, no scientific evidence is available concerning effectiveness of treatment. PURPOSE The purpose of the present study was to clinically evaluate possible effects of the proposed physiotherapeutic effects compared to observa...
متن کاملOsteochondral Abnormalities: Pitfalls, Injuries, and Osteochondritis Dissecans
Osteochondral lesions most commonly occur about the knee but may affect any articular surface of the pediatric appendicular skeleton. Osteochondral lesions include osteochondritis dissecans, osteochondral fractures, and osteochondral abnormalities associated with secondary processes such as Legg-Calvé-Perthes disease. These abnormalities should not be confused with normal subchondral irregulari...
متن کامل