A general strategy for the preparation of C-terminal peptide alpha-ketoacids by solid phase peptide synthesis.
نویسندگان
چکیده
A new cyanosulfur-ylide based linker makes possible the synthesis of C-terminal peptide alpha-ketoacids by solid phase synthesis. The preparation of the requisite linker and its application to a variety of C-terminal peptide alpha-ketoacids with unprotected side chains is reported.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 7 11 شماره
صفحات -
تاریخ انتشار 2009