An Autopsy Case Of Disseminated Nocardiosis Involving Multiple Organs Associated With Chemotherapy-induced Lung Damage Following Lung Cancer Surgery
نویسندگان
چکیده
The patient was a 71-year-old man. Two months after using prednisolone at a dose of 80 mg/day for the treatment of drug-induced interstitial pneumonia induced by chemotherapy following lung cancer surgery, his chest x-ray fi lm showed cavitary shadows, and Nocardia farcinica was detected from subcutaneous abscess, sputum, urine, and blood cultures. Thus, disseminated nocardiosis involving multiple organs was diagnosed. Despite treatment with a combination of trimethoprim-sulfamethoxazole and imipenem/cilastatin, the patient died of alveolar hemorrhage. In cases with steroid-induced immunosuppression, caution is necessary for the prevention of not only tuberculosis and pneumocystis jirovecii pneumonia, but also other infectious diseases including nocardiosis.
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