A novel method for sample delivery and testing of whole blood: gel strip PCR for point of care (POC) molecular diagnostics.

Validating a point of care lactate meter in adult patients with sepsis presenting to the emergency department of a tertiary care hospital of a low- to middle-income country.

BACKGROUND Timely identification of high blood lactate levels in septic patients may allow faster detection of those patients requiring immediate resuscitation. Point-of-care (POC) testing is being increasingly utilized in the emergency department (ED). We examined the accuracy and time-saving effect of a handheld POC lactate device for the measurement of fingertip and whole blood lactate as co...

A novel thermostable polymerase for RNA and DNA loop-mediated isothermal amplification (LAMP)

Meeting the goal of providing point of care (POC) tests for molecular detection of pathogens in low resource settings places stringent demands on all aspects of the technology. OmniAmp DNA polymerase (Pol) is a thermostable viral enzyme that enables true POC use in clinics or in the field by overcoming important barriers to isothermal amplification. In this paper, we describe the multiple advan...

How Much Can We Save the Cost from Shifting from Single - Test Strip to Multiple - Test Strip in Point of Care Testing Analysis for Common Clinical Chemistry Parameters ?

Microfluidics and point-of-care testing.

In many ways, the intrinsic features of microfluidics are a natural fit for a pointof-care (POC) diagnostics device (i.e. a diagnostic test performed near the patient without needing a clinical lab): low consumption of reagents and sample, miniaturization of device, and fast turnaround time for analysis. Thus, it comes as no surprise that much research, since the inception of modern microfluidi...

Molecular Testing for Toxoplasma Diagnosis in Aborted Fetuses- Taleghani Maternity Hospital- Arak- Iran

Background: The diagnosis of toxoplasmosis is most critical in pregnant women who acquire infection during gestation and also in fetuses and newborns who are congenitally infected. This study described the performance of molecular and confirmatory serologic testing for toxoplasma infection in the tissues of human spontaneous aborted fetuses and their mothers' blood. Materials and Methods...