Partial unilateral lentiginosis with Lisch nodules: a forme fruste of segmental neurofibromatosis?
نویسنده
چکیده
A 21-year-old female presented with multiple hyperpigmented macules on the left side of the face of 17 years’ duration. Hyperpigmented macules were noticed on the left side of the cheek at the age of 4 years, which gradually progressed to involve the left half of the face, neck, chest and upper back. No history of photosensitivity was present. There was no history of epilepsy, mental retardation or a family history of similar illness. The patient gave a history of easy fatiguability since childhood.
منابع مشابه
Peeling skin syndrome
The coexistence of neurofibromatosis with partial unilateral lentigines raises the possibility that partial unilateral lentigines could be a variant or forme fruste of segmental neurofibromatosis. Our patient had no cutaneous lesions of neurofibromatosis but had bilateral Lisch nodules in the eyes. Since Lisch nodules are characteristic of neurofibromatosis, we conclude that the partial unilate...
متن کاملMultiple, Unilateral Lisch Nodules in the Absence of Other Manifestations of Neurofibromatosis Type 1
Lisch nodules associated with Neurofibromatosis Type 1 (NF1) are usually multiple and bilateral in nature. Here, we report a 21-year-old healthy, Caucasian female who was diagnosed with multiple, unilateral Lisch nodules during routine eye examination. A thorough history and physical examination revealed no other signs of NF1. We diagnosed the rare occurrence of numerous, unilateral Lisch nodul...
متن کاملSegmental Neurofibromatosis Type 1, a Rare Variant of Neurofibromatosis: Report of Two Cases
Segmental neurofibromatosis type I (SNF-I) is a rare variant of neurofibromatosis (NF). It is classified as NF type V and defined as cafe'-au-lait macules and/or neurofibromas in a single ,unilateral segment of the body .We report two cases with SNF-I with striking similar manifestations.
متن کاملClinical and genetic patterns of neurofibromatosis 1 and 2.
General introduction to the neurofibromatoses The diseases traditionally known as neurofibromatosis have now been formally separated into two types: neurofibromatosis type 1 or NFl (the type described by von Recklinghausen) and neurofibromatosis type 2 or NF2 (a much rarer form).' It is now recognised that although they have overlapping features, including an inherited propensity to neurofibrom...
متن کاملConcomitant Occurrence of Segmental Neurofibromatosis and Lung Adenocarcinoma
Neurofibromatosis type 1 (NF1) caused by a loss-of functional mutation in NF1 encoding neurofibromin is an autosomal dominant disorder characterized by café-au-lait spots, neurofibromas, intertriginous freckles, and Lisch nodules. Segmental neurofibromatosis (SN) represents a postzygotic mutation and loss of heterozygosity in neurofibromin. SN occurring in the elder persons may be associated wi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Indian journal of dermatology, venereology and leprology
دوره 70 2 شماره
صفحات -
تاریخ انتشار 2004