Defective in vitro suppressor cell function in idiopathic congestive cardiomyopathy.
نویسندگان
چکیده
Because abnormalities of the immune system may be involved in the pathogenesis of idiopathic congestive cardiomyopathy (ICCM), we studied suppressor cell function in patients with ICCM. Previously described in vitro techniques were modified for optimal demonstration of concanavalin A (con A)-inducible suppressor activity by peripheral blood mononuclear cells (PBM). Baseline responses in the mixed leukocyte reaction (MLR) were similar for PBM from 16 normal subjects, eight patients with end-stage coronary artery dis-
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ورودعنوان ژورنال:
- Circulation
دوره 59 3 شماره
صفحات -
تاریخ انتشار 1979