Brucella abortus agglutinins in the sera of pregnant women and blood donors.

نویسندگان

  • H G BARTRAM
  • P W BOTHWELL
  • W H JEBB
  • A McDIARMID
  • A E PRESTON
چکیده

The incidence of brucellosis in the human population of England and Wales is still not accurately known, although estimates have been made (Wilson, 1932; Dalrymple-Champneys, 1950). Few persons who acquire Br. abortus develop any obvious clinical disease, but the existence of Br. abortus agglutinins in blood sera indicates past exposure to the organism. A survey of human and animal brucellosis made between 1957 and 1959 in the Oxford area (Bothwell, 1960 a, b, c, 1961; McDiarmid, 1960a, b, 1961) included the examination of 3,431 sera samples from pregnant women and of 8,690 samples of sera from blooddonorsforthepresenceofBr.abortusagglutinins. Both types of sera are readily available; both have limitations for survey purposes. Blood donor serum cannot be regarded as a normal sample compared with a cross-section of the general population, since blood donors are in fact highly-selected healthy persons. The serum from pregnant women also constitutes a selected sample. The incidence of agglutinins in both samples may represent an underestimate of the incidence of agglutinins in the general population. The results of both surveys are given, with notes on the investigation of milk supplies consumed by pregnant women with agglutinins to Br. abortus.

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عنوان ژورنال:
  • British journal of preventive & social medicine

دوره 17  شماره 

صفحات  -

تاریخ انتشار 1963