Toxicity and Antioxidant Tests of Morinda citrifolia (noni) Seed Extract
نویسندگان
چکیده
The aim of the current study was to evaluate Morinda citrifolia (noni) seed extract, a food ingredient, for potential toxicity and antioxidant activity. Nitrates, nitrites, phytic acid, oxalic acid, as well as aflatoxins B1, B2, G1 and G2 were not detected in the extract. The extract was also non-cytoxic (LC50 > 1 mg/mL) in the 24 and 40 h brine shrimp toxicity test. There were no symptoms of toxicity in a subacute (28 day) oral toxicity test in Sprague-Dawley rats. Noni seed extract did not display any genotoxic potential in a primary DNA damage test in E. coli PQ37. The extract did exhibit significant antioxidant activity in the Oxygen Radical Absorbance Capacity (ORAC) and Ferric Reducing Antioxidant Power (FRAP) tests.
منابع مشابه
Wound Healing and Antioxidant Activities of Morinda Citrifolia Leaf Extract In Rats
Morinda citrifolia (Noni) has been traditionally used for bone and wound healing. The present study was carried out to investigate the effect of Morinda citrifolia leaves on experimental wounds and lipid peroxide levels in rats. Effect of aqueous extract of leaves of Morinda citrifolia (200 mg/kg) on excision, resutured incision and dead space wound models were studied. Measurement...
متن کاملCancer preventive effect of Morinda citrifolia (Noni).
Morinda citrifolia (Noni) has been extensively used in folk medicine by Polynesians for over 2,000 years. It has been reported to have broad therapeutic effects, including anticancer activity, in both clinical practice and laboratory animal models. The mechanism for these effects remains unknown. The hypothesis that Morinda citrifolia possesses a cancer preventive effect at the initiation stage...
متن کاملHypolipidemic effect of seed oil of noni (Morinda citrifolia).
Morinda citrifolia, has been reported to posses different biological activities and almost all parts of this have been studied phytochemically. However there are few studies on the seeds of fruit. The objective of present study was investigated the effect to Noni Seed Oil (NSO) on serum lipid levels in normolipidemic and hyperlipidemic induced mice. We find that administration of noni oil cause...
متن کاملThin Layer Chromatography Methods for Rapid Identity Testing of Morinda citrifolia L. (Noni) Fruit and Leaf
Morinda citrifolia L., commonly known as noni, is a growing global commodity. As such , there is a need for rapid and inexpensive identity tests of noni fruit and leaf products. Thin Layer Chromatography (TLC) methods w ere developed for the identification of deacetylasperulosidic acid in noni fruit and leaf products. TLC methods were also developed for the identification of scopoletin in noni ...
متن کاملSafety tests and antinutrient analyses of noni (Morinda citrifolia L.) leaf.
BACKGROUND Noni (Morinda citrifolia L.) leaves have a documented history of food use. However, previous safety and antinutrient studies are absent. The current investigation was conducted to assess the utility of noni leaves as food. RESULTS No evidence of toxicity or differences in weight gain were observed in acute, subacute, and subchronic oral toxicity tests of ethanol-water (1:1 v/v) and...
متن کامل