Effects of A.C.T.H. on a case of tuberculous meningitis.

Although there are published references to over 200 cases of tuberculous meningitis treated with A.C.T.H., cortisone, or hydrocortisone, very few authors describe the effects of these hormones on patients with over 1 % protein in the C.S.F. Kendig, Choy and Johnson (1956) gave cortisone to a child during two periods when her C.S.F. protein was above 5 g. %; the protein content fell below 1 g. within a fortnight each time, and increased again when the first course of cortisone was stopped. Paraf, Paraf and Rapaud (1954) gave A.C.T.H. to patients whose C.S.F. contained up to 3 g. protein/ 100 ml., but their results, although encouraging, were only reported very briefly.