ACCF and AHA Presidents' Letter on MEDCAC.

نویسندگان

  • David R Holmes
  • Gordon F Tomaselli
  • Lisa Bradfield
چکیده

ventricular lead placement, whereas Bogaard et al. measured dp/dtmax after implantation and a guided approach may explain ifferences in remodeling and outcome. In keeping with our esults, optimal left ventricular lead positioning produces marked ariation in acute dp/dtmax (3), better remodeling, and reduced events (heart failure hospitalizations/death) (4). It is also important to appreciate that remodeling may not always correlate with clinical outcome especially in ischemic cardiomyopathy patients. Bogaard et al. (2) reported clinical outcome and remodeling or hospitalization for heart failure. Data were not consistently available or reported (nearly 50% of deaths were noncardiac or unknown) and they state that whether acute improvement in dP/dtmax correlates to morbidity still needs to be determined (2). In summary, we are in agreement with Prinzen et al. that a prospective randomized controlled study will be needed to confirm a favorable effect of LVdP/dtmax-guided therapy on prognosis and functional status after cardiac resynchronization therapy.

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عنوان ژورنال:
  • Journal of the American College of Cardiology

دوره 59 13  شماره 

صفحات  -

تاریخ انتشار 2012