Human antigen and enzyme markers in man-Chinese hamster somatic cell hybrids: evidence for synteny between the HL-A, PGM3, ME1, and IPO-B loci.

نویسندگان

  • H van Someren
  • A Westerveld
  • A Hagemeijer
  • J R Mees
  • P Meera Khan
  • O B Zaalberg
چکیده

In man-Chinese hamster somatic cell hybrids the segregation of the loci for 27 human enzyme markers and the species-specific surface antigens, including the HL-A histocompatibility antigens, was studied. The results show a synteny of the human loci for phosphoglucomutase 3, cytoplasmic malic enzyme, tetrameric indophenol oxidase, and HL-A. Furthermore, evidence is presented that the loci for the human species-specific antigens are distributed over several chromosomes.

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عنوان ژورنال:
  • Proceedings of the National Academy of Sciences of the United States of America

دوره 71 3  شماره 

صفحات  -

تاریخ انتشار 1974