Horizons in Biochemistry and Biophysics Series
نویسنده
چکیده
J. Knoll D e p a r t m e n t of P h a r m a c o l o g y , Semmelweis U n i v e r s i t y of M e d i a n e , Budapest, H u n g a r y K.D. Kohn L a b o r a t o r y of B i o c h e m i c a l P h a r m a c o l o g y , N a t i o n a l I n s t i t u t e of A r t h r i t i s , M e t a b o l i s m a n d D i g e s t i v e Diseases, N a t i o n a l I n s t i t u t e s of H e a l t h , Bethesda, M a r y l a n d , U.S.A. H. L . Kornberg, F.R.S. D e p a r t m e n t of B i o c h e m i s t r y , U n i v e r s i t y of C a m b r i d g e , E n g l a n d
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Computational Identification of Micro RNAs and Their Transcript Target(s) in Field Mustard (Brassica rapa L.)
Background: Micro RNAs (miRNAs) are a pivotal part of non-protein-coding endogenous small RNA molecules that regulate the genes involved in plant growth and development, and respond to biotic and abiotic environmental stresses posttranscriptionally.Objective: In the present study, we report the results of a systemic search for identifi cation of new miRNAs in B. rapa using homology-based ...
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Objective(s):Alzheimer's disease (AD) is the most common age-related neurodegenerative disorder. One of the hallmarks of AD is an abnormal accumulation of fibril forms of tau protein which is known as a microtubule associated protein. In this regard, inhibition of tau aggregation has been documented to be a potent therapeutic approach in AD and tauopathies. Unfortunately, the available syntheti...
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Compound action potential (CAP) of spinal cord represents valuable properties of neural fibers including excitability, rate of myelination and membrane integrity. These properties are measured using amplitude, latency and area under curve of CAPs recorded from spinal cord. Here, the isolated spinal cord was set in a double sucrose gap (DSG) chamber and its response to intracellular stimulation ...
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Anthracycline antibiotics are potent anticancer drugs widely used in the treatment of solidtumors and hematological malignancies. Because of their extensive clinical use and their toxiceffect on normal cells, in the present study the effect of these drugs on multipotent hematopoieticbone marrow cells was investigated employing, viability tests, PARP cleavage, Hoechst 33258staining, DNA fragment...
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Objective(s): Crocin, as the main carotenoid of saffron, has shown anti-tumor activity both in vitro and in vivo. Crocin might interact with cellular proteins and modulate their functions, but the exact target of this carotenoid and the other compounds of the saffron have not been discovered yet. Microtubular proteins, as one of the most important proteins inside the cells, have several functio...
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