Bisphosphonates induced Osteonecrosis of the Jaw: A review
نویسندگان
چکیده
Bisphosphonate therapy is used extensively to treat osteoporosis and osteolytic bone lesions. Recently, a special form of osteonecrosis limited to the maxillofacial skeleton has been discovered especially with the use of IV nitrogen containing Bisphosphonates. Bisphosphonates accumulate almost exclusively in maxillofacial skeleton due to high bone turnover remodeling to maintain mechanical competence. The pathogenesis, and why it commonly appears in maxillofacial skeletons, and the fixed treatment strategies remains unknown. The aim of this study was to improve the clinician understanding of Bisphosphonates associated osteonecrosis of the jaws by reviewing the past 10 year literature.
منابع مشابه
Jaw Osteonecrosis in Patients Receiving Oral Bisphosphonates Therapy
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