Magnitude of dental delay in trisomy G.
نویسندگان
چکیده
Previous reports have suggested delayed dental development in Down's syndrome (mongolism), but without quantification and without exclusion of subjects with cretinism, with a normal chromosomal complement, or with translocations and mosaics of various sorts. Accordingly, the tooth formation of 25 subjects with Down's syndrome, verified as trisomy G by karyotyping and excluding subjects with cretinism, was studied radiographically. Standards for tooth formation (crown calcification, root elongation, and alveolar eruption) were those previously described (S. M. GARN, A. B. LEWIS, and D. L. POLACHECK, Science, 128: 1510, 1958; S. M. GARN, A. B. LEWIS, and D. L. POLACHECK, I Dent Res 38:135-148, 1959; S. M. GARN, A. B. LEWIS, and R. M. BLIZZARD, 1 Dent Res 44:243-258, 1965). Dental age assessments were compared to exact chronological ages, calculated from actual birth dates. As shown in the Illustration, trisomy G is associated with delayed calcification, root development, and alveolar eruption (seen in obliqueand lateral-jaw views). Of the 25 subjects studied, 19 had delayed tooth formation, 3 had formation equal in dental and chronological age, and 3 had slightly advanced formation for age and sex. Against the chance hypothesis the distribution yielded a chi-square value of 11.6 for the 19:3 distribution as against the 11:11 hypothesis. The average delay was 0.7 years, a difference significant at
منابع مشابه
Relative magnitudes of crown size reduction and body size reduction in 47-trisomy G.
Since crown size reduction has been observed in 47-trisomy G (M. M. COHEN and R. A. WINER, J Dent Res 44:197-208, 1965; M. M. COHEN, S. M. GARN, and M. A. GECIAUSKAS, J Dent Res 49:460, 1970) with delayed tooth formation timing (S. M. GARN, C. W. STIMSON, and A. B. LEWIS, J Dent Res 49:640, 1970), it is useful to compare the magnitude of crown size reduction with the magnitude of body size redu...
متن کاملReport of a Case with Trisomy 9 Mosaicism
Trisomy 9 is a rare chromosome disorder with high neonatal mortality. It is often seen in mosaic form. Most patients who survive are severely mentally retarded. The main features of this syndrome are "bulbous" nose, microphthalmia, dislocated limbs, and other anomalies of skeletal, cardiac, genitourinary, and central nervous system. Most patients have developmental and cognitive impairment. Pat...
متن کاملIncreased crown-size asymmetry in trisomy G.
Trisomy G (Down's syndrome or "mongolism") is associated with multiple dental abnormalities (J. OSTER, Mongolism, Copenhagen: Danish Science Press, 1953). Teeth are frequently missing, all morphologic classes are involved, and the remaining teeth are characterized by size reduction (M. M. COHEN and A. WINER, I Dent Res 44:197-208, 1965; and M. M. COHEN, S. M. GARN, and M. A. GECIAUSKAS, J Dent ...
متن کاملDental management of a child with trisomy 9 mosaicism: a case report.
This case report presents the dental management of a 13-year-old girl with mosaic trisomy 9. She had: (1) severe psychomotor retardation; (2) short stature; (3) progressive microcephaly; (4) flat feet; (5) genu valgum; and (6) severe kyphoscoliosis. Dysmorphic facial features included: (1) maxillary prognathism; (2) narrow high-arched palate; (3) short philtrum; (4) small low posterior dysplast...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of dental research
دوره 49 3 شماره
صفحات -
تاریخ انتشار 1970