Rapid Access to Spirocyclized Indolenines via Palladium-Catalyzed Cascade Reactions of Tryptamine Derivatives and Propargyl Carbonate
نویسندگان
چکیده
We report the intermolecular palladium-catalyzed reaction of tert-butyl propargyl carbonate with tryptamine derivatives or other indole-containing bis-nucleophiles. The reaction proceeds under mild conditions and with low catalyst loadings to afford novel spiroindolenine products in good to high yields.
منابع مشابه
Palladium-catalyzed highly efficient synthesis of tetracenes and pentacenes.
Pd(0)-catalyzed cascade reactions of 1,7-diyn-3,6-bis(propargyl carbonate) with organoboronic acids have been developed, which provide one-pot access to functionalized tetracenes or pentacenes.
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