The oriented development of antituberculotics: salicylanilides.
نویسندگان
چکیده
On the basis of our previous results 22 salicylanilides were synthesized. The compounds were tested for in vitro antimycobacterial activity against Mycobacterium tuberculosis, Mycobacterium kansasii, and Mycobacterium avium. The Free-Wilson method was used to evaluate structure-antimycobacterial activity relationships. 4-Chloro-N-(4-propylphenyl)salicylamide and 5-chloro-N-(4-propylphenyl)salicylamide were selected for preclinical studies.
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ورودعنوان ژورنال:
- Archiv der Pharmazie
دوره 339 11 شماره
صفحات -
تاریخ انتشار 2006