Is cytomegalovirus a therapeutic target in glioblastoma?
نویسندگان
چکیده
Several investigators have now demonstrated the expression of genes unique to cytomegalovirus (CMV) in malignant gliomas. Many of these genes promote oncogenesis, alter tumor microenvironment, and serve as immunologic targets. Is the level of CMV infection within tumor cells sufficient to drive important oncogenic or immunosuppressive processes? Can CMV serve as a target for therapeutic intervention?
منابع مشابه
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عنوان ژورنال:
- Clinical cancer research : an official journal of the American Association for Cancer Research
دوره 17 14 شماره
صفحات -
تاریخ انتشار 2011