Increased haematuria in nephritis during cortisone and A.C.T.H. administration.

In the past few years cortisone and A.C.T.H. have been used in the treatment of nephritis. In the nephrotic state these drugs frequently produce a diuresis (Farnsworth, 1950a; Luetscher, Deming and Johnson, 1951). In haemorrhagic nephritis, however, the results have been variable (Thorn, Merrill, Smith, Roche and Frawley, 1950; Heller, Jacobson and Hammarsten, 1951). The present paper reports an increase in the urinary red cell excretion which was observed in two cases of haemorrhagic nephritis which were treated with cortisone and A.C.T.H., and in one case, of doubtful diagnosis but thought to be haemorrhagic nephritis, treated with A.C.T.H.