Simulating the formation of keratin lament networks by a piecewise-deterministic Markov process

نویسندگان

  • Michael Beil
  • Sebastian Lück
  • Frank Fleischer
  • Stéphanie Portet
  • Wolfgang Arendt
  • Volker Schmidt
چکیده

Keratin intermediate lament networks are part of the cytoskeleton in epithelial cells. They were found to regulate viscoelastic properties and motility of cancer cells. Due to unique biochemical properties of keratin polymers, the knowledge of the mechanisms controlling keratin network formation is incomplete. A combination of deterministic and stochastic modeling techniques can be a valuable source of information since

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تاریخ انتشار 2008