Chromatin remodeling and developmental gene regulation by thyroid hormone receptor Review Article
نویسندگان
چکیده
_________________________________________________________________________________________________ *Correspondence: Yun-Bo Shi, Building 18T, Rm. 106, NICHD, NIH, Bethesda MD, 20892; Tel: (301)-402-1004; Fax: (301)-4021323; E-mail: [email protected]
منابع مشابه
The N-CoR complex enables chromatin remodeler SNF2H to enhance repression by thyroid hormone receptor.
Unliganded thyroid hormone receptor (TR) actively represses transcription via the nuclear receptor corepressor (N-CoR)/histone deacetylase 3 (HDAC3) complex. Although transcriptional activation by liganded receptors involves chromatin remodeling, the role of ATP-dependent remodeling in receptor-mediated repression is unknown. Here we report that SNF2H, the mammalian ISWI chromatin remodeling AT...
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