Kynurenic acid prevented social recognition deficits induced by MK-801 in rats.
نویسندگان
چکیده
MK-801 impaired social recognition potency of adult male rats when given immediately after the initial interaction with a juvenile rat. Administration of kynurenic acid prior to the initial interaction protected the adults against recognition deficits induced by MK-801. When re-exposed at a delay of 30 min to the familiar juvenile, social investigation in the adults was significantly reduced. Thus, the adults are able to remember olfactory stimuli emitted by juvenile con-specifics.
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ورودعنوان ژورنال:
- Physiological research
دوره 52 6 شماره
صفحات -
تاریخ انتشار 2003