Development and evaluation of an Individualised Outcome Measure (IOM) for randomised controlled trials in mental health

Pesola, Francesca and Williams, Julie and Bird, Victoria and Freidl, Marion and Le Boutillier, Clair and Leamy, Mary and Macpherson, Rob and Slade, Mike (2015) Development and evaluation of an Individualised Outcome Measure (IOM) for randomised controlled trials

Development and evaluation of an Individualized Outcome Measure (IOM) for randomized controlled trials in mental health.

Pre-defined, researcher-selected outcomes are routinely used as the clinical end-point in randomized controlled trials (RCTs); however, individualized approaches may be an effective way to assess outcome in mental health research. The present study describes the development and evaluation of the Individualized Outcome Measure (IOM), which is a patient-specific outcome measure to be used for RCT...

Blindness in Randomized Controlled Trials

In combination with randomization, blinding or masking is an important factor in randomized controlled trials (RCTs), particularly in trials that assess therapeutic effects. Here an attempt is made to explain blindness and why it is important. In clinical trials, blinding is defined as the condition imposed on a study in which study participants, health care providers and assessors collecting o...

A systematic review of randomised clinical trials of individualised herbal medicine in any indication.

AIM To summarise and critically evaluate the evidence from randomised clinical trials for the effectiveness of individualised herbal medicine in any indication. METHODS Search of electronic databases and approaches to experts in the field to identify randomised, controlled clinical trials of individualised herbal medicine in any indication. Independent data extraction and assessment of method...

P-78: A Randomised Placebo-Controlled Trial to Determine the Effect of Iron Supplementation on Neonatal Outcome in Pregnant Women with Normal Heamoglobin (Hb=11-13

Background: To study the effect of iran supplementation on neonal outcom in pregnant women with normal heamoglobin (Hb=11g/dl )13 g/dl Methods : two handrad pregnant women with Hb=11-13 g/dl in the early slage of pregmancy? Materials and Methods: Each woman look one tablet of 50 mg of ferrossalphate daily in the case group (n=100) and placebo group (n=100). Results: While no significant differe...