Alpha-fetoprotein producing pulmonary blastoma in a patient with systemic sclerosis: pathogenetic analysis.

نویسندگان

  • I Kasuga
  • D Miyamoto
  • Y Ichinose
  • W Chimangul
  • K Minemura
  • K Utsumi
  • M Yonemaru
  • H Serizawa
  • Y Ebihara
  • K Toyama
چکیده

We describe a rare case of pulmonary blastoma complicated with systemic sclerosis. The serum alpha-fetoprotein level was elevated at presentation and the biopsied tumour stained positively against anti-alpha-fetoprotein antibody. The alpha-fetoprotein produced autonomously by tumour cells was of yolk-sac origin. Although the pathogenesis of pulmonary blastoma has not been clarified, we suggest that this pulmonary blastoma is a type of yolk-sac tumour.

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عنوان ژورنال:
  • The European respiratory journal

دوره 11 5  شماره 

صفحات  -

تاریخ انتشار 1998