the Development of Monocytic Lineage - Myristoyltransferase 1 in N Requirement of
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Requirement of N-myristoyltransferase 1 in the development of monocytic lineage.
N-myristoyltransferase (NMT) exists in two isoforms, NMT1 and NMT2, that catalyze myristoylation of various proteins crucial in signal transduction, cellular transformation, and oncogenesis. We have recently demonstrated that NMT1 is essential for the early development of mouse embryo. In this report, we have demonstrated that an invariant consequence of NMT1 knock out is defective myelopoesis....
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