Regular Article CLINICAL TRIALS AND OBSERVATIONS Ibritumomab consolidation after 3 cycles of CHOP plus radiotherapy in high-risk limited-stage aggressive B-cell lymphoma: SWOG S0313

نویسندگان

  • Daniel O. Persky
  • Thomas P. Miller
  • Joseph M. Unger
  • Catherine M. Spier
  • Soham Puvvada
  • B. Dino Stea
  • Oliver W. Press
  • Louis S. Constine
  • Kevin P. Barton
  • Jonathan W. Friedberg
  • Michael LeBlanc
  • Richard I. Fisher
چکیده

University of Arizona Cancer Center, University of Arizona, Tucson, AZ; SWOG Statistical Center, Fred Hutchinson Cancer Research Center, Seattle, WA; Department of Pathology, University of Arizona, Tucson, AZ; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA; James P. Wilmot Cancer Center, University of Rochester, Rochester, NY; Loyola University Medical Center, Maywood IL; and Fox Chase Cancer Center–Temple Health, Philadelphia, PA

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CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS CHOP is superior to CNOP in elderly patients with aggressive lymphoma while outcome is unaffected by filgrastim treatment: results of a Nordic Lymphoma Group randomized trial

This study was designed to test the hypothesis that administration of granulocyte colony-stimulating factor (G-CSF; filgrastim) during induction chemotherapy with CHOP (cyclophosphamide, vincristine, doxorubicin, prednisone) or CNOP (doxorubicin replaced with mitoxantrone) in elderly patients with aggressive nonHodgkin lymphoma (NHL) improves time to treatment failure (TTF), complete remission ...

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تاریخ انتشار 2014