Management of cytomegalovirus infection in haemopoietic stem cell transplantation.
نویسندگان
چکیده
Department of Virology, University College London School of Life and Medical Sciences, London, Department of Virology, King’s College Hospital, London, Department of Haematology, Freeman Road Hospital, Newcastle, West of Scotland specialist virology centre, Gartnavel General Hospital, Glasgow, Birmingham HPA Laboratory, Birmingham Heartlands Hospital, Birmingham, Department of Haematology, King’s College Hospital, London, Section of Haemato-oncology, The Royal Marsden NHS Foundation Trust, London, Department of Haematology, University College London Hospitals, London, and Blood and Marrow Transplant Unit, Beatson Oncology Centre, Glasgow, UK
منابع مشابه
Cytomegalovirus viral load and mortality after haemopoietic stem cell transplantation in the era of pre-emptive therapy: a retrospective cohort study
Methods In this retrospective cohort study, we included patients from the Fred Hutchinson Cancer Research Center, WA, USA, who received an allogeneic haemopoietic stem cell transplantation between Jan 1, 2007, and Feb 28, 2013, were cytomegalovirus seropositive or had a seropositive donor, and underwent weekly plasma cytomegalovirus monitoring by PCR through to day 100 post-transplantation. Cox...
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BACKGROUND Although cytomegalovirus viral load is commonly used to guide pre-emptive therapy in the post-transplantation setting, few data are available correlating viraemia with clinical endpoints. We therefore investigated the association between cytomegalovirus viral load and mortality in the first year after haemopoietic stem cell transplantation. METHODS In this retrospective cohort stud...
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Cytomegalovirus is related to high rates of morbidity and mortality after hematopoietic stem cell transplantation. This report highlights the importance of adequate monitoring and management of this infection. We report on two cases of patients with late subclinical cytomegalovirus infection. These patients were monitored for antigenemia by indirect immunofluorescence assay. Active cytomegalovi...
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BACKGROUND Human cytomegalovirus infection is the most frequent viral complication in patients undergoing hematopoietic stem cell transplantation. We investigated the development of human cytomegalovirus-specific T cells in adult recipients of hematopoietic stem cell transplants. DESIGN AND METHODS From May 2003 through October 2006 a total of 45 patients were monitored for human cytomegalovi...
متن کاملLong-term Outcome of Limbal Stem Cell Transplantation for the Management of Total Limbal Stem Cell Deficiency due to a Chemical Burn
Purpose: To evaluate the long-term outcome of limbal stem cell transplantation (LSCT) for the management of total limbal stem cell deficiency (LSCD) due to chemical burn in Labbafinejad Medical Center (LMC). Methods: Records of patients with a history of severe (i.e. grade III and IV) chemical burns, who were referred to LMC and underwent LSCT, were reviewed and data including demographic chara...
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ورودعنوان ژورنال:
- British journal of haematology
دوره 162 1 شماره
صفحات -
تاریخ انتشار 2013