Iron-mediated one-pot formal nitrocyclization onto unactivated alkenes.
نویسندگان
چکیده
One-pot synthesis of heterocycles having a nitromethyl group was achieved by sequential steps that involved chloronitration of alkenes using iron(III) nitrate nonahydrate followed by elimination and intramolecular Michael addition. This reaction provides an efficient method for the synthesis of heterocycles due to the simple experimental procedure and the use of inexpensive reagents of low toxicity.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 9 3 شماره
صفحات -
تاریخ انتشار 2011