A Pilot Study Evaluating Skin Toxicity in Radiation Treated Breast Cancer Patients Using RadiaPlexRxTM Topical Gel Containing 0.2% Hyaluronic Acid, Allantoin, and Aloe vera Extract
نویسنده
چکیده
An estimated 90% of breast cancer patients treated with radiotherapy will develop radiation dermatitis (Harper, 2004). Therapeutic doses of radiation cause persistent skin erythema, desquamation, rash, pain, itching and ulceration increasing risk of infection. Some clinicians suggest radiodermatitis be treated for the life of the patient because of collateral skin damage. Chemotherapy increases significantly the severity of acute radioepithelitis (Liguori, 1997). Skin toxicity results of 108 irradiated breast cancer
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Aloe vera (Aloe barbadensis, Aloe capensis).
BACKGROUND: Aloe vera, a succulent plant prevalent in hot, dry regions of Asia, Africa, and other areas, has been used in traditional medicine for many centuries. It is easily propagated in most places where the climate is hot and dry. The gel and dried latex obtained from aloe leaves are used for relief of constipation; for wound healing; and for treatment of burns, psoriasis, frostbite, ulcer...
متن کاملEffects of plant sterols derived from Aloe vera gel on human dermal fibroblasts in vitro and on skin condition in Japanese women
BACKGROUND Aloe is known for its topical use for treating wounds and burns. Many previous studies reported the healing effects of Aloe vera. However, there are few clinical studies on the effect of orally administered A. vera gel on the skin. Aloe sterols are a type of plant sterols that have the capability to regulate the metabolism of glucose and lipids. In a recent study, we confirmed that i...
متن کاملLack of Prophylactic Effects of Aloe Vera Gel on Radiation Induced Dermatitis in Breast Cancer Patients
Purpose: Radiotherapy induced dermatitis is a common and sometimes serious side effect. We conducted a randomized study to understand whether the adjunctive use of aloe vera gel might reduce the prevalence and/or severity of radiotherapy induced dermatitis. Methods: One hundred patients with newly diagnosed breast cancer were randomized to receive aloe vera gel or nothing during adjuvant radiot...
متن کاملAloe vera for preventing radiation-induced skin reactions: a systematic literature review.
AIM To systematically review and critically appraise the evidence for effectiveness of Aloe vera gel for radiation-induced skin reactions. MATERIALS AND METHODS Major biomedical databases and specialist complementary and alternative medicine databases were searched. Additionally, efforts were made to identify unpublished and ongoing research. Relevant research was systematically categorised b...
متن کاملAssessment of Anti HSV-1 Activity of Aloe Vera Gel Extract: an In Vitro Study
STATEMENT OF THE PROBLEM Herpes simplex virus (HSV) infection is one of the most common and debilitating oral diseases; yet, there is no standard topical treatment to control it. The extract of Aloe vera leaves has been previously reported to have anti-inflammatory, antibacterial, and also antiviral effects. There is no data on anti-Herpes simplex virus type 1 (HSV-1) activity of Aloe vera gel....
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