Fasting and post-methionine loading concentrations of homocysteine, vitamin B2, and vitamin B6 in patients on antiepileptic drugs.
نویسندگان
چکیده
Paediatr Suppl 1999;88:200–8. 21. Wajnrajch MP, Gertner JM, Mullis PE, Deladoëy J, Cogan JD, Lekhakula S, et al. ARGHIS is a new mutational “hot-spot” in the growth hormone (GH) gene causing isolated GH deficiency type II. J Endocr Genet 2001;1:125– 35. 22. Wada M, Uchida H, Ikeda M, Tsunekawa B, Naito N, Banba S, et al. The 20-kilodalton (kDA) human growth hormone (hGH) differs from the 22-kDA hGH in the complex formation with cell surface hGH receptor and hGHbinding protein circulating in human plasma. Mol Endocrinol 1997;12:146– 56. 23. Goffin V, Shiverick KT, Kelly PA, Martial JA. Sequence-function relationships within the expanding family of prolactin, growth hormone, placental lactogen, and related proteins in mammals. Endocr Rev 1996;17:385–410.
منابع مشابه
Low circulating folate and vitamin B6 concentrations: risk factors for stroke, peripheral vascular disease, and coronary artery disease. European COMAC Group.
BACKGROUND A high plasma homocysteine concentration is a risk factor for atherosclerosis, and circulating concentrations of homocysteine are related to levels of folate and vitamin B6. This study was performed to explore the interrelationships between homocysteine, B vitamins, and vascular diseases and to evaluate the role of these vitamins as risk factors for atherosclerosis. METHODS In a mu...
متن کاملThe effect of a subnormal vitamin B-6 status on homocysteine metabolism.
Homocysteine, an atherogenic amino acid, is either remethylated to methionine or metabolized to cysteine by the transsulfuration pathway. The biochemical conversion of homocysteine to cysteine is dependent upon two consecutive, vitamin B-6-dependent reactions. To study the effect of a selective vitamin B-6 deficiency on transsulfuration, we performed oral methionine load tests on 22 vitamin B-6...
متن کاملمقایسه سطح سرمی هموسیستیین در بیماران مبتلا به دیابت نوع 2 مصرف‌کننده متفورمین و گلی‌بن‌کلامید
Background: Diabetes mellitus is the most common cause of renal failure, blindness, non- traumatic amputation and neuropathy. Homocysteine, a sulfurated amino acid, has a close correlation with Methionine and Cysteine. The conversion of Methionine to Homocysteine and Cysteine is required coenzymes like vitamin B6, B12 and Folate. The effect of Metformin on serum Homocysteine level by decreasing...
متن کاملHyperhomocysteinemia: a risk factor for placental abruption or infarction.
OBJECTIVE To establish the prevalence of hyperhomocysteinemia in women with placental abruption or infarction. DESIGN Forty-six women with normal pregnancy outcome (controls) and 84 women with placental abruption or infarction (study group) were selected, and studied in the non-pregnant state. Homocysteine metabolism was investigated by a standardized oral methionine loading test. Hyperhomocy...
متن کاملTreatment of mild hyperhomocysteinemia in vascular disease patients.
Mild hyperhomocysteinemia is recognized as a risk factor for premature arteriosclerotic disease. A few vitamins and other substances have been reported to reduce blood homocysteine levels, but normalization of elevated blood homocysteine concentrations with any of these substances has not been reported. Therefore, we screened 421 patients suffering from premature peripheral or cerebral occlusiv...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Clinical chemistry
دوره 49 6 Pt 1 شماره
صفحات -
تاریخ انتشار 2003